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Lu Cai Selected Research

Fibrosis (Cirrhosis)

5/2024Withaferin A as a Potential Therapeutic Target for the Treatment of Angiotensin II-Induced Cardiac Cachexia.
2/2022Sex differences in the effects of whole-life, low-dose cadmium exposure on postweaning high-fat diet-induced cardiac pathogeneses.
6/2021Engineered cardiac tissues: a novel in vitro model to investigate the pathophysiology of mouse diabetic cardiomyopathy.
1/2021Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice.
1/2021KLF15 negatively regulates cardiac fibrosis by which SDF-1β attenuates cardiac fibrosis in type 2 diabetic mice.
1/2021Divergent Regulation of Alveolar Type 2 Cell and Fibroblast Apoptosis by Plasminogen Activator Inhibitor 1 in Lung Fibrosis.
10/2020Transcriptome profile analysis reveals a silica-induced immune response and fibrosis in a silicosis rat model.
8/2020Loss of NF-E2 expression contributes to the induction of profibrotic signaling in diabetic kidneys.
1/2020Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension.
1/2020Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function.
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Lu Cai Research Topics

Disease

59Inflammation (Inflammations)
01/2023 - 12/2008
50Fibrosis (Cirrhosis)
05/2024 - 12/2004
42Diabetic Cardiomyopathies
02/2024 - 01/2003
34Neoplasms (Cancer)
05/2024 - 03/2003
27Diabetic Nephropathies (Diabetic Nephropathy)
12/2023 - 02/2004
25Obesity
02/2023 - 12/2006
25Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2020 - 12/2009
24Type 2 Diabetes Mellitus (MODY)
10/2023 - 12/2008
23Insulin Resistance
02/2023 - 02/2011
19Hyperglycemia
10/2023 - 06/2002
18Cardiovascular Diseases (Cardiovascular Disease)
02/2023 - 01/2002
17Hypoxia (Hypoxemia)
12/2022 - 08/2007
16Diabetes Complications
12/2023 - 01/2007
16Body Weight (Weight, Body)
01/2022 - 01/2003
16Cardiomyopathies (Cardiomyopathy)
01/2020 - 01/2003
13Cardiomegaly (Heart Hypertrophy)
05/2024 - 04/2013
11Hypertrophy
02/2022 - 07/2010
10Hypertension (High Blood Pressure)
09/2023 - 01/2009
10Cardiotoxicity
11/2022 - 01/2002
8Breast Neoplasms (Breast Cancer)
01/2021 - 03/2013
7Fatty Liver
03/2024 - 01/2015
7Ischemia
10/2023 - 01/2003
7Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2023 - 12/2008
7Non-alcoholic Fatty Liver Disease
01/2023 - 01/2016
7Diabetes Mellitus
11/2021 - 10/2005
6Atherosclerosis
11/2022 - 01/2003
6Myocardial Infarction
10/2019 - 01/2002
5Heart Failure
01/2023 - 01/2014
5Necrosis
06/2021 - 01/2003
5Wounds and Injuries (Trauma)
07/2018 - 01/2008
4Liver Diseases (Liver Disease)
04/2024 - 01/2019
4Pulmonary Arterial Hypertension
11/2022 - 01/2020
4Heart Diseases (Heart Disease)
01/2021 - 01/2012
4Proteinuria
01/2019 - 04/2007
4Prostatic Neoplasms (Prostate Cancer)
01/2018 - 07/2011
4Hyperlipidemias (Hyperlipidemia)
01/2016 - 02/2004
3Cachexia
05/2024 - 10/2021
3Mitochondrial Diseases (Mitochondrial Disease)
01/2023 - 02/2010
3Myocardial Ischemia (Ischemic Heart Diseases)
03/2021 - 12/2014
3Hepatocellular Carcinoma (Hepatoma)
01/2021 - 03/2018
3Kidney Diseases (Kidney Disease)
01/2021 - 01/2015
3B-Cell Lymphoma (Lymphoma, B Cell)
12/2020 - 01/2017
3Pulmonary Fibrosis (Fibrosing Alveolitis)
10/2020 - 07/2011
3Chronic Disease (Chronic Diseases)
01/2020 - 01/2003

Drug/Important Bio-Agent (IBA)

36MetallothioneinIBA
10/2023 - 03/2003
32Glucose (Dextrose)FDA LinkGeneric
03/2024 - 06/2002
30Streptozocin (Streptozotocin)FDA Link
01/2021 - 01/2003
28ZincIBA
10/2023 - 01/2006
26AntioxidantsIBA
06/2021 - 01/2003
25Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2003
24LipidsIBA
11/2022 - 02/2004
19sulforaphaneIBA
10/2022 - 01/2012
14Insulin (Novolin)FDA Link
10/2023 - 06/2002
13CadmiumIBA
02/2023 - 10/2013
12CollagenIBA
05/2024 - 07/2005
12fibroblast growth factor 21IBA
01/2020 - 01/2011
10Plasminogen Activator Inhibitor 1IBA
01/2021 - 04/2007
9Messenger RNA (mRNA)IBA
01/2021 - 02/2010
8Therapeutic UsesIBA
01/2023 - 01/2008
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2022 - 01/2003
8Transcription Factors (Transcription Factor)IBA
01/2022 - 02/2011
8Reactive Oxygen Species (Oxygen Radicals)IBA
12/2019 - 01/2009
8Connective Tissue Growth FactorIBA
03/2017 - 02/2004
7Angiotensin IIIBA
05/2024 - 07/2011
7MetalsIBA
04/2024 - 03/2017
7Fibroblast Growth Factor 1 (FGF-1)IBA
01/2022 - 03/2007
7p38 Mitogen-Activated Protein KinasesIBA
01/2022 - 01/2010
7CytokinesIBA
01/2022 - 01/2003
7EnzymesIBA
01/2021 - 01/2003
7Phosphotransferases (Kinase)IBA
01/2019 - 11/2006
6Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
02/2022 - 12/2009
6Fibronectins (Fibronectin)IBA
02/2022 - 01/2013
6Caspase 3 (Caspase-3)IBA
06/2021 - 06/2002
6Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2021 - 01/2010
6IronIBA
12/2019 - 01/2008
6CurcuminIBA
01/2019 - 06/2014
6Small Interfering RNA (siRNA)IBA
02/2014 - 01/2010
5Atrial Natriuretic Factor (ANF)IBA
05/2024 - 04/2013
5Environmental Pollutants (Pollutants, Environmental)IBA
04/2024 - 03/2021
5Fenofibrate (CiL)FDA LinkGeneric
01/2020 - 04/2016
5Chelating AgentsIBA
12/2019 - 01/2008
5Biomarkers (Surrogate Marker)IBA
05/2019 - 11/2016
5Histones (Histone)IBA
01/2019 - 01/2014
4ArsenicIBA
11/2022 - 07/2013
4Transforming Growth Factors (Transforming Growth Factor)IBA
12/2021 - 01/2014
4Sirtuin 1IBA
03/2018 - 12/2014
4Blood Glucose (Blood Sugar)IBA
01/2016 - 01/2014
4Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2012 - 03/2007
3Advanced Glycation End ProductsIBA
06/2021 - 12/2004
3MicroRNAs (MicroRNA)IBA
01/2021 - 11/2013
3Triglycerides (Triacylglycerol)IBA
01/2021 - 01/2003
3Malondialdehyde (Propanedial)IBA
01/2021 - 01/2010
3Cisplatin (Platino)FDA LinkGeneric
01/2021 - 08/2013
3Fatty Acids (Saturated Fatty Acids)IBA
01/2021 - 01/2019
3PalmitatesIBA
01/2021 - 09/2016
3ResveratrolIBA
01/2019 - 10/2016

Therapy/Procedure

24Therapeutics
09/2023 - 01/2009
10Drug Therapy (Chemotherapy)
12/2022 - 03/2013
8Intraperitoneal Injections
01/2020 - 01/2003
6Radiotherapy
03/2024 - 01/2014